Skip to content

Commit b8ae3e4

Browse files
authored
Update references (#2650)
* NoordijkRei2025 * HuckJak2025
1 parent 9bd6ca2 commit b8ae3e4

File tree

2 files changed

+37
-1
lines changed

2 files changed

+37
-1
lines changed

doc/amici_refs.bib

Lines changed: 24 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -1456,6 +1456,30 @@ @Article{SmithMal2025
14561456
url = {https://www.biorxiv.org/content/early/2025/01/20/2025.01.16.633337},
14571457
}
14581458
1459+
@Article{NoordijkRei2025,
1460+
author = {Noordijk, Ben and Reinders, Marcel and van Dijk, Aalt D.J. and de Ridder, Dick},
1461+
journal = {bioRxiv},
1462+
title = {{BADDADAN}: Mechanistic Modelling of Time Series Gene Module Expression},
1463+
year = {2025},
1464+
abstract = {Plants respond to stresses like drought and heat through complex gene regulatory networks (GRNs). To improve resilience, understanding these is crucial, but large-scale GRNs (\>100 genes) are difficult to model using ordinary differential equations (ODEs) due to the high number of parameters that have to be estimated. Here we solve this problem by introducing BADDADAN, which uses machine learning to identify gene modules{\textemdash}groups of co-expressed and/or co-regulated genes{\textemdash}and constructs an ODE model that predicts gene module dynamics under stress. By integrating time-series gene expression data with prior co-expression data it finds modules that are both coherent and interpretable. We demonstrate BADDADAN on heat and drought datasets of A. thaliana, modelling over 1,000 genes, recovering known mechanistic insights, and proposing new hypotheses. By combining machine learning with mechanistic modelling, BADDADAN deepens our understanding of stressrelated GRNs in plants and potentially other organisms.Competing Interest StatementThe authors have declared no competing interest.},
1465+
creationdate = {2025-02-27T17:14:20},
1466+
doi = {10.1101/2025.02.18.638670},
1467+
elocation-id = {2025.02.18.638670},
1468+
eprint = {https://www.biorxiv.org/content/early/2025/02/23/2025.02.18.638670.full.pdf},
1469+
modificationdate = {2025-02-27T17:14:35},
1470+
publisher = {Cold Spring Harbor Laboratory},
1471+
url = {https://www.biorxiv.org/content/early/2025/02/23/2025.02.18.638670},
1472+
}
1473+
1474+
@Electronic{HuckJak2025,
1475+
author = {Wilhelm Huck and Miglė Jakštaitė and Tao Zhou and Frank Nelissen and Bob van Sluijs},
1476+
title = {Timed batch inputs unlock significantly higher yields for enzymatic cascades},
1477+
year = {2025},
1478+
creationdate = {2025-03-10T08:55:10},
1479+
doi = {10.21203/rs.3.rs-5917349/v1},
1480+
modificationdate = {2025-03-10T08:58:09},
1481+
}
1482+
14591483
@Comment{jabref-meta: databaseType:bibtex;}
14601484
14611485
@Comment{jabref-meta: grouping:

doc/references.md

Lines changed: 13 additions & 1 deletion
Original file line numberDiff line numberDiff line change
@@ -1,6 +1,6 @@
11
# References
22

3-
List of publications using AMICI. Total number is 95.
3+
List of publications using AMICI. Total number is 97.
44

55
If you applied AMICI in your work and your publication is missing, please let us know via a new
66
[GitHub issue](https://github.com/AMICI-dev/AMICI/issues/new?labels=documentation&title=Add+publication&body=AMICI+was+used+in+this+manuscript:+DOI).
@@ -15,6 +15,18 @@ If you applied AMICI in your work and your publication is missing, please let us
1515
<h1 class="unnumbered" id="section">2025</h1>
1616
<div id="refs" class="references csl-bib-body hanging-indent"
1717
role="list">
18+
<div id="ref-HuckJak2025" class="csl-entry" role="listitem">
19+
Huck, Wilhelm, Miglė Jakštaitė, Tao Zhou, Frank Nelissen, and Bob van
20+
Sluijs. 2025. <span>“Timed Batch Inputs Unlock Significantly Higher
21+
Yields for Enzymatic Cascades.”</span> 2025. <a
22+
href="https://doi.org/10.21203/rs.3.rs-5917349/v1">https://doi.org/10.21203/rs.3.rs-5917349/v1</a>.
23+
</div>
24+
<div id="ref-NoordijkRei2025" class="csl-entry" role="listitem">
25+
Noordijk, Ben, Marcel Reinders, Aalt D. J. van Dijk, and Dick de Ridder.
26+
2025. <span>“<span>BADDADAN</span>: Mechanistic Modelling of Time Series
27+
Gene Module Expression.”</span> <em>bioRxiv</em>. <a
28+
href="https://doi.org/10.1101/2025.02.18.638670">https://doi.org/10.1101/2025.02.18.638670</a>.
29+
</div>
1830
<div id="ref-SmithMal2025" class="csl-entry" role="listitem">
1931
Smith, Lucian, Rahuman S. Malik-Sheriff, Tung V. N. Nguyen, Henning
2032
Hermjakob, Jonathan Karr, Bilal Shaikh, Logan Drescher, et al. 2025.

0 commit comments

Comments
 (0)