diff --git a/fastdeploy/engine/args_utils.py b/fastdeploy/engine/args_utils.py
index 546d9de52a..633b6837c3 100644
--- a/fastdeploy/engine/args_utils.py
+++ b/fastdeploy/engine/args_utils.py
@@ -863,8 +863,6 @@ def create_engine_config(self) -> Config:
         graph_opt_cfg = self.create_graph_optimization_config()
         graph_opt_cfg.update_use_cudagraph(self.use_cudagraph)
 
-        assert not (self.use_cudagraph and self.enable_prefix_caching), "Prefix caching cannot be used with CUDA graph"
-
         assert not (
             self.tensor_parallel_size <= 1 and self.enable_custom_all_reduce
         ), "enable_custom_all_reduce must be used with tensor_parallel_size>1"
diff --git a/fastdeploy/engine/engine.py b/fastdeploy/engine/engine.py
index 5b555465e9..42963ee807 100644
--- a/fastdeploy/engine/engine.py
+++ b/fastdeploy/engine/engine.py
@@ -183,6 +183,7 @@ def start(self, api_server_pid=None):
                 engine_worker_queue_port=self.cfg.engine_worker_queue_port,
                 pid_suffix=self.ipc_signal_suffix,
             )
+            self.launched_cache_manager_signal.value[0] = 1
 
         self.worker_proc = self._start_worker_service()
         console_logger.info("Waitting worker processes ready...")
@@ -217,9 +218,6 @@ def start(self, api_server_pid=None):
         # Start TokenProcessor thread
         self.token_processor.run()
 
-        if self.do_profile:
-            self._stop_profile()
-
         if self.cfg.splitwise_role != "mixed":
             # 单机逻辑
             self.engine_worker_queue.available_prefill_instances.put(1)
@@ -849,6 +847,17 @@ def _init_worker_signals(self):
             create=True,
         )
 
+        # launched_cache_manager_signal 用于感知engine是否启动了cache_manager
+        if self.cfg.cache_config.enable_prefix_caching or self.cfg.splitwise_role != "mixed":
+            launched_cache_manager_signal_data = np.zeros([1], dtype=np.int32)
+            self.launched_cache_manager_signal = IPCSignal(
+                name="launched_cache_manager_signal",
+                array=launched_cache_manager_signal_data,
+                dtype=np.int32,
+                suffix=self.ipc_signal_suffix,
+                create=True,
+            )
+
         # worker_live_signal 用于engine感知各worker进程是否存活，记录每个step 时间
         worker_healthy_live_recorded_time_array = np.zeros(shape=[self.cfg.worker_num_per_node], dtype=np.int32)
         self.worker_healthy_live_signal = IPCSignal(
@@ -1133,6 +1142,7 @@ def _stop_profile(self):
                 engine_worker_queue_port=self.cfg.engine_worker_queue_port,
                 pid_suffix=self.ipc_signal_suffix,
             )
+            self.launched_cache_manager_signal.value[0] = 1
 
     def check_health(self, time_interval_threashold=30):
         """
@@ -1171,6 +1181,10 @@ def detect_thread():
 
         self.checking_worker_status_thread = threading.Thread(target=detect_thread, daemon=True)
         self.checking_worker_status_thread.start()
+        checking_worker_init_kv_cache_status_thread = None
+        if self.do_profile:
+            checking_worker_init_kv_cache_status_thread = threading.Thread(target=self._stop_profile, daemon=True)
+            checking_worker_init_kv_cache_status_thread.start()
 
         # display weight loadding progress
         with tqdm(total=100, desc="Loading Weights") as pbar:
@@ -1201,6 +1215,8 @@ def detect_thread():
         self.worker_init_status["finished"] = True
         try:
             self.checking_worker_status_thread.join(timeout=1)
+            if checking_worker_init_kv_cache_status_thread is not None:
+                checking_worker_init_kv_cache_status_thread.join(timeout=1)
         except Exception:
             pass
         return True
diff --git a/fastdeploy/worker/gcu_model_runner.py b/fastdeploy/worker/gcu_model_runner.py
index b58c2237fe..406ce53d98 100644
--- a/fastdeploy/worker/gcu_model_runner.py
+++ b/fastdeploy/worker/gcu_model_runner.py
@@ -151,8 +151,6 @@ def insert_prefill_inputs(self, req_dicts: List[Request]):
         """
         Process inputs for prefill tasks and insert it to share_inputs buffer
         """
-        if "caches" not in self.share_inputs:
-            self.initialize_kv_cache()
 
         if req_dicts[-1].disaggregate_info is not None and req_dicts[-1].disaggregate_info["role"] == "prefill":
             os.environ["PREFILL_NODE_ONE_STEP_STOP"] = "1"
@@ -561,7 +559,7 @@ def update_parameters(self, pid):
         self.initialize_kv_cache()
         self.dynamic_weight_manager._log_memory("dynamic weight manager update all memory")
 
-    def initialize_kv_cache(self) -> None:
+    def initialize_kv_cache(self, profile: bool = False) -> None:
         """
         Initialize kv cache
         """
@@ -582,7 +580,7 @@ def initialize_kv_cache(self) -> None:
         kv_cache_shape = self.attn_backends[0].get_kv_cache_shape(max_num_blocks=max_block_num)
         # local_rank = self.local_rank % self.parallel_config.tensor_parallel_size
 
-        if not self.parallel_config.do_profile and (
+        if not profile and (
             self.parallel_config.enable_prefix_caching or self.parallel_config.splitwise_role != "mixed"
         ):
             raise NotImplementedError("prefix_caching is not support by GCUModelRunner.")
@@ -1012,7 +1010,7 @@ def profile_run(self) -> None:
 
         # Initialize kv cache for profile run. After profile run kv cache will be reset.
         self.num_gcu_blocks = self.parallel_config.total_block_num
-        self.initialize_kv_cache()
+        self.initialize_kv_cache(profile=True)
 
         # 1. Profile with multimodal encoder & encoder cache
 
@@ -1038,8 +1036,7 @@ def update_share_input_block_num(self, num_gpu_blocks: int) -> None:
         self.num_gcu_blocks = num_gpu_blocks
 
         # Reset block table and kv cache with global block num
-        if not (self.parallel_config.enable_prefix_caching or self.parallel_config.splitwise_role != "mixed"):
-            self.initialize_kv_cache()
+        self.initialize_kv_cache()
 
         # Reset free list
         free_list = list(
@@ -1057,8 +1054,6 @@ def update_share_input_block_num(self, num_gpu_blocks: int) -> None:
             }
         )
 
-        self.parallel_config.do_profile = False
-
         if self.speculative_method in ["mtp"]:
             self.proposer.update_block_num(num_gpu_blocks)
 
diff --git a/fastdeploy/worker/gcu_worker.py b/fastdeploy/worker/gcu_worker.py
index 2e4e83885b..1b98e3b0c8 100644
--- a/fastdeploy/worker/gcu_worker.py
+++ b/fastdeploy/worker/gcu_worker.py
@@ -98,9 +98,9 @@ def get_model(self) -> nn.Layer:
         """ """
         return self.model_runner.get_model()
 
-    def initialize_cache(self, num_gpu_blocks: int, num_cpu_blocks: int) -> None:
+    def initialize_cache(self, num_gpu_blocks: int) -> None:
         """ """
-        pass
+        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
 
     def execute_model(
         self,
@@ -134,7 +134,3 @@ def check_health(self) -> bool:
     def cal_theortical_kvcache(self) -> int:
         """ """
         return self.model_runner.cal_theortical_kvcache()
-
-    def reinitialize_kv_cache(self, num_gpu_blocks: int) -> None:
-        """ """
-        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
diff --git a/fastdeploy/worker/gpu_model_runner.py b/fastdeploy/worker/gpu_model_runner.py
index 0d199c57d2..710ecaff34 100644
--- a/fastdeploy/worker/gpu_model_runner.py
+++ b/fastdeploy/worker/gpu_model_runner.py
@@ -193,9 +193,6 @@ def insert_prefill_inputs(self, req_dicts: List[Request]):
         Process inputs for prefill tasks and insert it to share_inputs buffer
         TODO(gongshaotian): Refactor this func
         """
-        # NOTE(luotingdan): Lazy initialize kv cache
-        if "caches" not in self.share_inputs:
-            self.initialize_kv_cache()
 
         # NOTE(luotingdan): Set environment variable of prefill node
         if req_dicts[-1].disaggregate_info is not None and req_dicts[-1].disaggregate_info["role"] == "prefill":
@@ -700,7 +697,7 @@ def initialize_forward_meta(self):
         for attn_backend in self.attn_backends:
             attn_backend.init_attention_metadata(self.forward_meta)
 
-    def initialize_kv_cache(self) -> None:
+    def initialize_kv_cache(self, profile: bool = False) -> None:
         """
         Initialize kv cache
         """
@@ -721,7 +718,7 @@ def initialize_kv_cache(self) -> None:
         kv_cache_shape = self.attn_backends[0].get_kv_cache_shape(max_num_blocks=max_block_num)
         local_rank = self.local_rank % self.parallel_config.tensor_parallel_size
 
-        if not self.parallel_config.do_profile and (
+        if not profile and (
             self.parallel_config.enable_prefix_caching or self.parallel_config.splitwise_role != "mixed"
         ):
             cache_kvs_list = []
@@ -739,7 +736,6 @@ def initialize_kv_cache(self) -> None:
 
         else:
             for i in range(self.model_config.num_hidden_layers):
-
                 cache_kvs[f"key_caches_{i}"] = paddle.full(
                     shape=kv_cache_shape,
                     fill_value=0,
@@ -1218,7 +1214,7 @@ def profile_run(self) -> None:
         # Initialize kv cache for profile run. After profile run kv cache will be reset.
         # TODO(gongshaotian): Optimize the management logic of kvcache
         self.num_gpu_blocks = self.parallel_config.total_block_num
-        self.initialize_kv_cache()
+        self.initialize_kv_cache(profile=True)
 
         # 1. Profile with multimodal encoder & encoder cache
 
@@ -1243,8 +1239,7 @@ def update_share_input_block_num(self, num_gpu_blocks: int) -> None:
         self.num_gpu_blocks = num_gpu_blocks
 
         # Reset block table and kv cache with global block num
-        if not (self.parallel_config.enable_prefix_caching or self.parallel_config.splitwise_role != "mixed"):
-            self.initialize_kv_cache()
+        self.initialize_kv_cache()
 
         # Reset free list
         free_list = list(
@@ -1262,8 +1257,6 @@ def update_share_input_block_num(self, num_gpu_blocks: int) -> None:
             }
         )
 
-        self.parallel_config.do_profile = False
-
         if self.speculative_method in ["mtp"]:
             self.proposer.update_block_num(num_gpu_blocks)
 
diff --git a/fastdeploy/worker/gpu_worker.py b/fastdeploy/worker/gpu_worker.py
index 45aa96b4c1..812b62935a 100644
--- a/fastdeploy/worker/gpu_worker.py
+++ b/fastdeploy/worker/gpu_worker.py
@@ -165,9 +165,10 @@ def get_model(self) -> nn.Layer:
         """Get current model"""
         return self.model_runner.get_model()
 
-    def initialize_cache(self, num_gpu_blocks: int, num_cpu_blocks: int) -> None:
-        """Initizlize the KV Cache"""
-        pass
+    def initialize_cache(self, num_gpu_blocks: int) -> None:
+        """Initizlize the KV Cache with accurate num_gpu_blocks"""
+        # accurate cache size
+        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
 
     def execute_model(
         self,
@@ -198,7 +199,3 @@ def check_health(self) -> bool:
     def cal_theortical_kvcache(self) -> int:
         """Calculate the block memory required"""
         return self.model_runner.cal_theortical_kvcache()
-
-    def reinitialize_kv_cache(self, num_gpu_blocks: int) -> None:
-        """Reinitialize the kv cache using the parameters from the profile"""
-        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
diff --git a/fastdeploy/worker/iluvatar_model_runner.py b/fastdeploy/worker/iluvatar_model_runner.py
index 1bce9d19e2..54d6600d32 100644
--- a/fastdeploy/worker/iluvatar_model_runner.py
+++ b/fastdeploy/worker/iluvatar_model_runner.py
@@ -141,9 +141,6 @@ def insert_prefill_inputs(self, req_dicts: List[Request]):
         Process inputs for prefill tasks and insert it to share_inputs buffer
         TODO(gongshaotian): Refactor this func
         """
-        # NOTE(luotingdan): Lazy initialize kv cache
-        if "caches" not in self.share_inputs:
-            self.initialize_kv_cache()
 
         # NOTE(luotingdan): Set environment variable of prefill node
         if req_dicts[-1].disaggregate_info is not None and req_dicts[-1].disaggregate_info["role"] == "prefill":
@@ -552,7 +549,7 @@ def clear_cache(self):
         if self.forward_meta is not None:
             self.forward_meta.clear_caches()
 
-    def initialize_kv_cache(self) -> None:
+    def initialize_kv_cache(self, profile: bool = False) -> None:
         """
         Initialize kv cache
         """
@@ -992,7 +989,7 @@ def profile_run(self) -> None:
         # Initialize kv cache for profile run. After profile run kv cache will be reset.
         # TODO(gongshaotian): Optimize the management logic of kvcache
         self.num_gpu_blocks = self.parallel_config.total_block_num
-        self.initialize_kv_cache()
+        self.initialize_kv_cache(profile=True)
 
         # 1. Profile with multimodal encoder & encoder cache
 
@@ -1016,8 +1013,7 @@ def update_share_input_block_num(self, num_gpu_blocks: int) -> None:
         self.num_gpu_blocks = num_gpu_blocks
 
         # Reset block table and kv cache with global block num
-        if not (self.parallel_config.enable_prefix_caching or self.parallel_config.splitwise_role != "mixed"):
-            self.initialize_kv_cache()
+        self.initialize_kv_cache()
 
         # Reset free list
         free_list = list(
@@ -1035,8 +1031,6 @@ def update_share_input_block_num(self, num_gpu_blocks: int) -> None:
             }
         )
 
-        self.parallel_config.do_profile = False
-
     def cal_theortical_kvcache(self):
         """
         Calculate the total block memory required at the model level
diff --git a/fastdeploy/worker/iluvatar_worker.py b/fastdeploy/worker/iluvatar_worker.py
index f855466ffc..76fcb558bc 100644
--- a/fastdeploy/worker/iluvatar_worker.py
+++ b/fastdeploy/worker/iluvatar_worker.py
@@ -99,9 +99,9 @@ def get_model(self) -> nn.Layer:
         """ """
         return self.model_runner.get_model()
 
-    def initialize_cache(self, num_gpu_blocks: int, num_cpu_blocks: int) -> None:
+    def initialize_cache(self, num_gpu_blocks: int) -> None:
         """ """
-        pass
+        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
 
     def execute_model(
         self,
@@ -135,7 +135,3 @@ def check_health(self) -> bool:
     def cal_theortical_kvcache(self) -> int:
         """ """
         return self.model_runner.cal_theortical_kvcache()
-
-    def reinitialize_kv_cache(self, num_gpu_blocks: int) -> None:
-        """ """
-        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
diff --git a/fastdeploy/worker/worker_base.py b/fastdeploy/worker/worker_base.py
index 0d604c2e05..281776bb0e 100644
--- a/fastdeploy/worker/worker_base.py
+++ b/fastdeploy/worker/worker_base.py
@@ -64,7 +64,7 @@ def init_device(self) -> None:
         raise NotImplementedError
 
     @abstractmethod
-    def initialize_cache(self, num_gpu_blocks: int, num_cpu_blocks: int) -> None:
+    def initialize_cache(self, num_gpu_blocks: int) -> None:
         """Initizlize the KV Cache with the given size in blocks."""
         raise NotImplementedError
 
diff --git a/fastdeploy/worker/worker_process.py b/fastdeploy/worker/worker_process.py
index d656f60ae9..96503fd800 100644
--- a/fastdeploy/worker/worker_process.py
+++ b/fastdeploy/worker/worker_process.py
@@ -347,7 +347,7 @@ def event_loop_normal(self) -> None:
 
             self.exist_prefill_task_signal.value[0] = self.worker.prefill_finished()
 
-    def determine_num_available_blocks(self) -> None:
+    def initialize_kv_cache(self) -> None:
         """Profiles the peak memory usage of the model to determine how many
         KV blocks may be allocated without OOMs.
 
@@ -400,8 +400,25 @@ def determine_num_available_blocks(self) -> None:
                 self.get_profile_block_num_signal.value[0] = num_blocks_local
         else:
             num_blocks_local = self.fd_config.parallel_config.total_block_num
-        # 4. Updata share inputs
-        self.worker.reinitialize_kv_cache(num_gpu_blocks=num_blocks_local)
+
+        logger.info(f"------- num_blocks_global: {num_blocks_local} --------")
+        # wait engine launch cache_manager
+        if self.parallel_config.enable_prefix_caching or self.parallel_config.splitwise_role != "mixed":
+            launched_cache_manager_signal_data = np.zeros([1], dtype=np.int32)
+            self.launched_cache_manager_signal = IPCSignal(
+                name="launched_cache_manager_signal",
+                array=launched_cache_manager_signal_data,
+                dtype=np.int32,
+                suffix=self.parallel_config.engine_pid,
+                create=False,
+            )
+            while np.any(self.launched_cache_manager_signal.value[0] <= 0):
+                time.sleep(0.01)
+        # 4. init kv_cache with accurate num_blocks
+        self.worker.initialize_cache(num_gpu_blocks=num_blocks_local)
+
+    def graph_optimize_and_warm_up_model(self) -> None:
+        self.worker.graph_optimize_and_warm_up_model()
 
     def init_device(self) -> None:
         """Initialize device and Construct model runner"""
@@ -714,8 +731,8 @@ def run_worker_proc() -> None:
 
     # Load model
     worker_proc.load_model()
-    logger.info("determine_num_available_blocks")
-    worker_proc.determine_num_available_blocks()
+    # Initialize KV Cache
+    worker_proc.initialize_kv_cache()
 
     # Trigger CUDAGraph capture
     worker_proc.worker.graph_optimize_and_warm_up_model()
diff --git a/fastdeploy/worker/xpu_worker.py b/fastdeploy/worker/xpu_worker.py
index 8ce43b4dd0..49b4a74ac0 100644
--- a/fastdeploy/worker/xpu_worker.py
+++ b/fastdeploy/worker/xpu_worker.py
@@ -131,9 +131,9 @@ def get_model(self) -> nn.Layer:
         """ """
         return self.model_runner.get_model()
 
-    def initialize_cache(self, num_gpu_blocks: int, num_cpu_blocks: int) -> None:
+    def initialize_cache(self, num_gpu_blocks: int) -> None:
         """ """
-        pass
+        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)
 
     def execute_model(
         self,
@@ -159,7 +159,3 @@ def preprocess_new_task(self, req_dicts: List[Request]) -> None:
     def check_health(self) -> bool:
         """ """
         return True
-
-    def reinitialize_kv_cache(self, num_gpu_blocks: int) -> None:
-        """ """
-        self.model_runner.update_share_input_block_num(num_gpu_blocks=num_gpu_blocks)