RuntimeError: mat1 and mat2 shapes cannot be multiplied (111556x92 and 103x64)

[mj72git]

Hi
I want to design binder for my target. My code:

python /app/RFdiffusion/scripts/run_inference.py
inference.input_pdb=/app/data/inputs/e.pdb
inference.output_prefix=/app/data/outputs/E_complex_model
inference.num_designs=1
'contigmap.contigs=[E24-357/0,50-80]'
'ppi.hotspot_res=[E250,E251,E252,E253,E254,E255,E256,E257,E258,E259]'
diffuser.T=15
inference.ckpt_override_path=/app/RFdiffusion/models/Complex_Fold_base_ckpt.pt
denoiser.noise_scale_ca=0
denoiser.noise_scale_frame=0

but error: RuntimeError: mat1 and mat2 shapes cannot be multiplied (111556x92 and 103x64)

[WAI272]

I'm not too much sure but maybe It's because of pdb or contig. For contig you may try replacing "," with " ". In pdb case for my usage I didn't use hetatms and water, maybe this was the issue.

[rclune]

Can you provide input and output files so that we can try to recreate your issue? I'm not sure what's creating your issue, but the more information you give the better we can diagnose it.

A few notes, please ignore if you chose these values for specific reasons:

• Setting the noise scale for the CA and frame to 0 is not recommended, this will reduce the diversity of your designs.
• Having 15 timesteps is a bit small, the smallest number I have seen recommended is 20.

[mj72git]

My input (target protein) is three chains of a CRISPR. I received this error while I using (inference.ckpt_override_path=/app/RFdiffusion/models/Complex_Fold_base_ckpt.pt) I cant write my code without this.

[rclune]

So it will run with other checkpoint files?