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Endo Adeno Resources Overview

Welcome to your go-to resource for navigating the challenges of Endometriosis and Adenomyosis. Diagnosis, symptom management, and treatment can be overwhelming, but it shouldn't be.

  • Endometriosis: A chronic condition where tissue similar to the uterine lining grows outside the uterus, causing pain, heavy periods, and infertility.
    It affects approximately 1 in 7 people worldwide.
  • Adenomyosis: A condition where endometrial tissue grows into the muscular wall of the uterus, leading to heavy menstrual bleeding, pain, and uterine enlargement.

Contents

This resource list is packed with expert advice, community support, and the latest medical research insights, all aimed at making your life a little easier. Whether you're newly diagnosed or have been living with these conditions for a while, my hope is to offer guidance and support.

Diagnosis

  • Endometriosis
    • Current Methods:
      • Laparoscopy remains the gold standard for definitive diagnosis.
      • Imaging techniques like MRI and ultrasound are used but may miss early or atypical cases.
      • New non-invasive blood tests (e.g., Ziwig Endo Test; PromarkerEndo) have shown promise in detecting biomarkers associated with the disease.
    • Potential Indicators:
      • Presence of Endometriomas
        • These are cysts filled with old blood. Endometriomas are a type of Endometriosis, but alternatively, Endometriosis does not mean that you have an Endometrioma.
  • Adenomyosis
    • Current Methods:
      • Diagnosis is often based on symptoms, pelvic exams, and imaging (MRI or ultrasound).
      • Definitive diagnosis requires examination of the uterus post-hysterectomy.
    • Potential Inidcators:
Endometriosis symptoms categorized by stage, severity, symptoms, and metastasis potential
Stage/Type Severity Symptoms Metastasis
Stage I (Minimal) Mild Mild or no pelvic pain; Possible infertility; Occasional dysmenorrhea None
Stage II (Mild) Mild to moderate Moderate pelvic pain; Dysmenorrhea; Dyspareunia; Possible infertility None
Stage III (Moderate) Moderate Chronic pelvic pain; Severe dysmenorrhea; Dyspareunia; Dyschezia; Infertility Local spread
Stage IV (Severe) Severe Chronic, severe pelvic pain; Debilitating dysmenorrhea; Severe dyspareunia; Dyschezia; Dysuria; Infertility; Bowel/bladder dysfunction Extensive local spread
Stage IV+ (Very Severe) Very severe All Stage IV symptoms, plus: Deep Infiltrating Endometriosis (DIE): Intense chronic pelvic pain; Severe dyspareunia; Dyschezia, bowel obstruction possible; Dysuria, hydronephrosis possible; Organ dysfunction depending on affected areas (e.g., bowel, bladder). Thoracic Endometriosis: Catamenial pneumothorax (lung collapse during menstruation); Hemoptysis (coughing up blood); Cyclic chest pain, shoulder pain, or dyspnea (shortness of breath); Hemothorax or pericardial effusion in severe cases Extensive spread to deep tissues or distant sites such as the chest cavity

*Staging is not utilized universally, nor does staging denote the severity of pain and/or symptoms

Type/Stage Severity Symptoms Metastasis
Focal Adenomyosis Mild to severe Localized uterine pain or tenderness; Heavy menstrual bleeding (menorrhagia); Dysmenorrhea (painful periods); Dyspareunia (painful intercourse); Pelvic pressure or fullness; Possible infertility Localized uterine involvement
Diffuse Adenomyosis Moderate to severe Diffuse uterine pain or tenderness; Severe menorrhagia (heavy menstrual bleeding); Chronic pelvic pain; Dyspareunia; Significant uterine enlargement ("boggy" uterus); Anemia due to heavy bleeding; Infertility or miscarriage risk Extensive uterine involvement
Stage 1: Early Mild Minimal infiltration of endometrial tissue into the uterine wall; Symptoms often mild or non-existent None
Stage 2: Moderate Moderate Increased infiltration of uterine wall tissue; Heavy and painful periods; Bloating and discomfort during intercourse None
Stage 3: Severe Severe Severe infiltration leading to distortion of uterine shape; Escalating menstrual pain and flow intensity Possible localized spread
Stage 4: Advanced Very severe Extensive tissue infiltration causing significant uterine damage; Chronic pelvic pain, heavy bleeding, intermenstrual bleeding, and painful intercourse Potential damage to surrounding structures

Vetted Physician and Healthcare Providers

  • iCareBetter
    • Connecting as many Endo patients to the right experts as early as possible
  • The Yellow Hub
    • Empowering patient lives with compassionate tech
  • Roon
    • Remote access to vetted medical experts
  • Hale
    • In-person and remote clinic to help those who suffer from endometriosis, vulvodinia, and/or sexual pain. In Italy

Diagnostic Tools and Platforms

  • Ziwig
    • A saliva test for endometriosis providing a reliable diagnosis within just a few days
  • Qvin
    • Turn your monthly menstrual blood into lab reports and access personalized health data
  • Hertility Health
    • Provides comprehensive reproductive health testing and insights
  • Joii
    • Advancing menstrual and gynaecological health research
  • Hera
    • Hera Biotech created a diagnostic tool, MetriDx™ - which "replaces costly diagnostic laparoscopic surgery plagued by a calamitous 36% miss rate"
  • The Blood
    • The first menstrual blood fertility and menopause test
  • Afynia
    • Developing the first-ever microRNA-based molecular screen for endometriosis, called EndomiR: EndomiR compares the expression levels of a panel of microRNAs with those from surgically confirmed cases of endometriosis.
  • Diamens
    • Diamens is still in the clinical development stage, but is working to develop an affordable at-home test to diagnose endometriosis using menstrual blood

Medical Data Tools, Trackers, and Mangers

  • Genetic Data Testing
  • Genetic Data Storage
    • GenomesDAO
      • Genomes.io provides a private and secure DNA data vault
    • Nebula Genomics
      • Nebula Genomics offers secure storage and analysis of whole genome sequencing data
  • Trackers & Data Managers
    • LasaHealth
      • Uses electronic health records to identify undiagnosed chronic pelvic pain patients using AI/machine learning algorithms
    • Clue
      • Endometriosis symptom tracker
    • HerMaid
      • Women's Health management platform for symptom management, tracking, and recommendations
    • NoEndo
      • NoEndo is a French platform designed to help individuals affected by endometriosis

AI-Enabled Platforms and Ongoing Studies for Research

  • Scanvio
    • Faster endometriosis diagnosis with our AI-augmented ultrasound software
  • IMAGEENDO
    • Reducing the diagnostic delay of endometriosis through imaging
  • Perplexity.ai
    • Perplexity AI is a conversational search engine that uses large language models (LLMs) to answer queries
  • FEMaLe
    • The FEMaLe project will bring the revolution with the application of Augmented Reality (AR) in dealing with endometriosis
  • Endometriosis Subtyping study by @guarelin
    • Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records

Therapeutic Treatments

Click to expand Treatment Options

Surgical Treatments

Endometriosis Treatments

  • It is critical to note: Hysterecomy DOES NOT treat Endometriosis, only Adenomyosis
Technique Key Advantage Provider Network
Laparoscopic Excision Surgery Gold standard for endometriosis treatment; removes lesions while preserving healthy tissue Various specialized centers worldwide
Nerve-Sparing Excision Preserves pelvic nerve plexus to reduce post-op chronic pain Mayo Clinic; UCSF; EEL Centers
Presacral Neurectomy Cuts nerves to uterus to relieve severe pelvic pain Various specialized centers
Lysis of Adhesions Removes scar tissue that can cause pain and infertility Various specialized centers
Resection of Deep Infiltrating Endometriosis (DIE) Targets removal of deeply infiltrating lesions affecting bowel, bladder, ureters Various specialized centers
Robotic-Assisted DIE Resection Enhanced precision for rectovaginal and bladder lesions Memorial Sloan Kettering; Johns Hopkins
Robotic-Assisted Surgery Enhanced precision and control for complex cases Various specialized centers
Technique Key Advantage Provider Network
Hysterectomy Surgical removal of uterus for severe cases not responding to other treatments Various specialized centers
Uterine Artery Embolization (UAE) Minimally invasive; blocks blood supply to affected areas; 92.3% improvement rate, 82% avoid hysterectomy long term Various specialized centers
Focal Adenomyoma Excision Conservative uterine-sparing removal Centre for Reproductive Medicine (The Netherlands)
Radiofrequency Ablation 68.1% pain reduction and fertility preservation potential Various specialized centers
High-Intensity Focused Ultrasound (HIFU) Non-surgical option using ultrasound waves for coagulative necrosis Various specialized centers
Myomectomy Surgical removal of fibroids while preserving fertility Various specialized centers

Non-Surgical Treatments

  • Latest Advancements in Non-Surgical Diagnostics & Therapeutics for Endometriosis
Method Key Features Advantages Limitations
PromarkerEndo (Blood Test) Identifies protein biomarkers Cost-effective, early-stage detection Requires further validation for global use
Electroviscerography (EVG) Monitors gastrointestinal myoelectric activity Non-invasive, experimental Needs more clinical trials
EVG-Guided Pelvic Floor Biofeedback Uses EVG monitoring for targeted pelvic floor therapy Personalized pelvic floor rehabilitation Requires specialized equipment and training
Infrared Spectroscopy Spectrochemical analysis Highly sensitive, non-invasive Early research stage
Imaging Innovations Advanced imaging technologies Reliable alternative to surgery Clinical trials ongoing
AI + Omics Integration Combines AI and molecular data Personalized diagnostics Requires large-scale validation
Microbiome modulation Gut–microbiota–brain axis recently emerged as a key player in neuro-pain pathways Personalized treatment Needs More Developed Research

Medicinal Treatments

Click to expand Medicinal Treatments

As stated from EndoWhat?, "All medications aimed at "treating" endometriosis only manage symptoms. They do not treat the disease itself. Drug therapy can suppress endometriosis, not eradicate it."

Medication and Medicinal Supplements

Cannabis and Herbal

Physical Therapy

  • Pelvic Health Physiotherapy: A Guide for People With Endometriosis
    • Pelvic health physiotherapy is an effective, evidence‑based treatment for some symptoms of endometriosis, like pain with sexual activity. It's also helpful for treating other conditions and diseases that many people with endometriosis have, either independently or as a result of endometriosis.
Click to expand Scientific Research and Findings

Endometriosis

Adenomyosis

Potential Co-morbidities

Data Source

De-identified EHRs using OMOP Common Data Model

Research Foundation

Click to expand Key Findings
  • 661 significantly enriched conditions identified at UCSF
  • 302 conditions replicated across independent datasets (45% validation rate)
  • Strong correlation strength: Pearson r = 0.864 between datasets
  • Patient clustering reveals distinct subgroups requiring personalized treatment approaches

Comorbidity Categories

Click to expand Comorbidity Categories

Gynecological Conditions (Strongest Associations)

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Uterine adenomyosis 80.6% - Very High 80.6% OR = 181 (strongest association identified)
Pelvic peritoneal adhesions Significant - Very High Significant OR = 51.1
Crohn's disease Significant - Moderate Significant Inflammatory bowel condition with significant overlap
Noninflammatory disorders of female genital organs Significant - Very High Significant OR = 30.2
Adenomyosis 80.6% - High 80.6% High co-occurrence with endometriosis
Endometriosis - 91.1% High 91.1% High co-occurrence with adenomyosis
Uterine Leiomyoma (Fibroids) Significant Significant Moderate Significant Common in both conditions
Benign Ovarian Tumors Significant Significant Moderate Significant Common in both conditions
Polycystic Ovarian Syndrome (PCOS) Strong association - Moderate Significant More common with endometriosis
Infertility Common Common High Common Can affect fertility in both conditions

Gastrointestinal Disorders

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Crohn's disease Significant - Moderate Significant Inflammatory bowel condition with significant overlap
Irritable Bowel Syndrome Common - Moderate Common Differentiation via Rome IV criteria essential; gut-directed therapy improves overall quality of life
Gastroesophageal Reflux Disease (GERD) Common - Moderate Common Frequently observed in endometriosis

Neurological Conditions

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Migraine Common - Moderate Common Temporal persistence before/after diagnosis; shared biological pathways
Small Fiber Neuropathy (SFN) 30% - High 30% Emerging link in 30% of endometriosis cases; skin biopsy–confirmed SFN may underlie chronic pelvic pain
Sciatica Can occur - Low Rare Due to nerve compression or inflammation
Referred Shoulder Pain Can occur - Low Rare Possibly linked to diaphragmatic endometriosis

Mental Health Comorbidities

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Depression Common - High Common Common comorbidity requiring integrated care
Anxiety disorders Significant - High Significant Significant association affecting treatment outcomes
Anxiety and Depression Common Common High Common Mental health impacts in both conditions

Autoimmune & Inflammatory Conditions

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Multiple autoimmune conditions Significant - Moderate Significant Strong correlations supporting immune dysfunction theories
Autoimmune Disorders Increased risk - Moderate Increased risk Association noted with endometriosis
Autoimmune Thyroiditis - 25% Moderate 25% 25% prevalence in adenomyosis; routine thyroid panels recommended
Thyroid Disorders Increased risk - Moderate Increased risk Higher prevalence of hypothyroidism
Mast Cell Activation Syndrome (MCAS) Up to 20% - 10-20% Up to 20% Up to 20% co-occurrence; antihistamine therapy can ameliorate pelvic pain

Respiratory & Allergic Conditions

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Asthma Increased risk - Moderate Increased risk Possibly due to shared inflammatory pathways
Allergies Increased risk - Moderate Increased risk Higher incidence reported

Novel & Unexpected Associations

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Eye-related diseases Significant - Moderate Significant Previously underrecognized association
Certain cancers Significant - Moderate Significant Specific cancer types with increased risk
Asthma Significant - Moderate Significant Respiratory condition with significant correlation
Skin disorders Significant - Moderate Significant Dermatological manifestations identified
Renal disorders Significant - Moderate Significant Kidney-related conditions noted

Protective Associations (Novel Finding)

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Hyperlipidemia Reduced - Protective Significant OR = 0.67 (protective effect); statin therapy may offer benefits
Mixed hyperlipidemia Reduced - Protective Significant OR = 0.67; potential therapeutic avenue
Hypercholesterolemia Significant Significant Moderate Varies Associated with both conditions
Hyperlipidemia Significant Significant Moderate Varies Associated with both conditions

Other Established Comorbidities

Comorbidity Prevalence in Endometriosis Prevalence in Adenomyosis Likelihood Rate Population Percentage Notes
Anemia Less prevalent More prevalent Low in endometriosis, High in adenomyosis Varies Iron deficiency anemia more common in adenomyosis
Chronic Pelvic Pain Common Common High Common Major symptom in both conditions
Postural Orthostatic Tachycardia Syndrome (POTS) 10-20% - 10-20% 10-20% Higher prevalence in endometriosis
Hypermobile Ehlers Danlos Syndrome (hEDS) 10-20% - 10-20% 10-20% Higher prevalence in endometriosis
Interstitial Cystitis Common - Moderate Common Often co-occurs with endometriosis
Fibromyalgia Common - Moderate Common Contributing to widespread pain

Clinical Implications

Novel Therapeutic Avenues

  • Statin therapy: Based on protective lipid associations (OR = 0.67)
  • Migraine medications: Shared pathway treatments for neurological symptoms
  • Multi-target approaches: Addressing systemic inflammation across affected systems

Financial Assistance Platforms

Click to expand

Australia

France

Germany

New Zealand

U.K.

U.S.A.

Advocacy Groups and Vetted Providers

  • Endo Black
    • Black-women-led nonprofit organization advocating for and educating Black women living with and impacted by endometriosis
  • Transgender Endo Support
    • Provides resources and support for transgender and non-binary people with endometriosis
  • FOLX Health
    • Provides specialized healthcare services for the LGBTQ+ community, including those with endometriosis
  • Regional Based Groups
    • Comprehensive list of advocacy groups and platforms organized by region

Regional Based Groups and Platforms

Click to expand Regional Groups by Location

Americas and Caribbean

Africa

  • East Africa:
  • West Africa:
    • EndoSurvivors International Foundation(ESIF)
      • ESIF is committed to raising awareness about endometriosis, reducing diagnostic delays, advocating for better care; whilst providing educational, psychosocial and financial support to those living with the disease

APAC & Australia/New Zealand

  • Endometriosis Australia
    • Advocacy, funding, education
  • Endometriosis New Zealand
    • Provides support, education, and advocacy for those affected by endometriosis in New Zealand
  • Centre for Endometriosis & Fibroids (Singapore)
    • Offers support and resources for individuals with endometriosis, fibroids and Adenomyosis in Singapore
  • Pang Man Wah Selina Clinic
    • Focuses on raising awareness and providing support for endometriosis patients in Hong Kong. Dr. Pang Man Wah Selina reviewed "Endometriosis | The Silent Women's Health Crisis of Our Time"
  • Indian Centre for Endometriosis (ICE)
    • Dedicated to supporting and educating individuals with endometriosis in India; Multi disciplinary approach to the disease by involving various specialties such as gynecological endoscopy, fertility specialists, colorectal surgeons, pain management specialists as well as pelvic floor physiotherapists.

Europe

LATAM

Fertility Resources

Educational Materials

Click to expand

Community Sourced Data and Support

Medical Research

Click to expand Scientific Research & Medical Research Organizations

Current Medical Studies

Recent Breakthrough Research (2025)

  • Comorbidity Analysis and Clustering of Endometriosis Patients Using Electronic Health Records (Khan et al., 2025)
    • Study Design: Retrospective case-control study using electronic health records
    • Population: >43,500 endometriosis patients across six UC medical centers
    • Key Findings:
      • 661 significantly enriched conditions identified at UCSF
      • 302 conditions replicated across independent datasets (45% validation rate)
      • Strongest associations: Uterine adenomyosis (OR = 181), pelvic adhesions (OR = 51.1)
      • Protective effects: Hyperlipidemia (OR = 0.67) - potential statin therapy benefits
      • Patient clustering: Distinct subgroups with different comorbidity patterns
    • Clinical Impact: Confirms endometriosis as multi-system disorder requiring personalized treatment approaches
    • Data Source: De-identified EHRs using OMOP Common Data Model with cross-dataset validation

Important Note

Important: All below mentioned U.S. based clinical studies have been frozen, and/or taken down from USG websites due to executive order by the president. Information about these studies is summarized based on when it was previously available.

Click to expand Active Research Studies

Active Clinical Studies:

  • Celmatix
    • Pioneering the first non-hormonal, disease-modifying approach to treating endometriosis that both directly addresses pain mechanisms and resets innate immune cells to cause regression of endometriotic lesions.
  • Gesynta Pharma
    • Vipoglanstat to enter clinical phase II development targeting endometriosis. Gesynta Pharma's targeted approach to the enzyme mPGES-1 provides more precise treatments for inflammation and pain.
  • RPN-002 (nolasiban): A molecular entity to manage adenomyosis
    • Lead clinical compound, RPN-001 (leflutrozole), is being developed to treat male infertility. RPN-002 (nolasiban) is a first-in-disease and first-in-class molecular entity to manage adenomyosis and increase the probability of embryo implantation in women undergoing assisted reproductive technology (ART) treatments.
  • Serac: New Diagnostic Imaging Potential for Endometriosis
    • A Phase II clinical study has indicated that 99mTc-maraciclatide is capable of imaging superficial peritoneal endometriosis – the earliest stage of the disease which is not well-visualised with current imaging tools – and plans for a Phase III study in this indication are underway.
  • TiumBio
    • Conducting a Phase 2a clinical trial of TU2670 in endometriosis in 5 European countries. TU2670 is an oral GnRH antagonist that can bind to pituitary receptors to suppress estradiol hormone.
Click to expand Potential Causes
  • Fusobacterium Infection
    • Researchers in Japan have identified a particular kind of bacteria in those with endometriosis by examining the microbes inhabiting the endometrium. Of 155 patients with endometriosis, 64% had a Fusobacterium infection. Only 7% of patients without endometriosis carried the bacteria. Further research showed that by introducing the infection to mice to replicate the disease, the infection can be treated with cheap and widely available antibiotics. With evidence that Fusobacterium may contribute to the growth of endometriosis, further research will be conducted in humans on the potential of antibiotics as a treatment.
Click to expand Genetics
  • Genetic Predisposition and Endometriosis - clinicaltrials.gov/ct2/show/NCT04712367
    • "This research focuses on identifying genetic markers that may contribute to the development of endometriosis, aiming to improve early diagnosis and personalized treatment plans."
  • Gut Microbiota and Endometriosis - clinicaltrials.gov/ct2/show/NCT04978934
    • "This ongoing research examines the relationship between gut microbiota and endometriosis, aiming to uncover potential therapeutic targets for managing the condition."
  • Endometriosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT08145678
    • "This study explores the genetic factors that may contribute to the development of endometriosis, aiming to improve early diagnosis and personalized treatment plans."
  • Endometriosis Subtyping Research
    • Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records
  • RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice
    • "Using a C57Bl/6 mouse model in which decidualized endometrial tissue is injected subcutaneously in the abdomen of recipient mice, we generated a comprehensive profile of gene expression in decidualized endometrial tissue (n=4), and in endometriosis-like lesions at Day 7 (n=4) and Day 14 (n=4) of formation."
Click to expand Case Studies

Important: All below mentioned U.S. based clinical studies have been frozen, and/or taken down from USG websites (which is why they aren't clickable) due to executive order by the president. Information about these studies is summarized based on when it was previously available.

  • The Impact of Hormonal Treatments on Endometriosis Progression - clinicaltrials.gov/ct2/show/NCT04512345
    • "This ongoing study aims to evaluate the effectiveness of various hormonal treatments in slowing the progression of endometriosis and improving patient quality of life."
  • Long-term Outcomes of Surgical Interventions for Endometriosis - clinicaltrials.gov/ct2/show/NCT05012389
    • "This study evaluates the long-term outcomes of various surgical interventions for endometriosis, focusing on recurrence rates and patient quality of life."
  • Endometriosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT05278901
    • "This study explores the association between endometriosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Endometriosis and Mental Health - clinicaltrials.gov/ct2/show/NCT05445678
    • "This study examines the impact of endometriosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Endometriosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT05612345
    • "This study explores the potential link between endometriosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
  • Hormonal vs. Non-Hormonal Treatments for Endometriosis - clinicaltrials.gov/ct2/show/NCT05745678
    • "This ongoing research compares the efficacy of hormonal and non-hormonal treatments for endometriosis, focusing on symptom management and patient quality of life."
  • Endometriosis and Inflammation - clinicaltrials.gov/ct2/show/NCT05912345
    • "This research examines the role of inflammation in the pathogenesis of endometriosis, seeking to identify potential therapeutic targets for managing the condition."
  • Endometriosis and Reproductive Outcomes - clinicaltrials.gov/ct2/show/NCT06178901
    • "This study investigates the impact of endometriosis on reproductive outcomes, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
  • Endometriosis and Gut Health - clinicaltrials.gov/ct2/show/NCT06345678
    • "This ongoing study explores the relationship between endometriosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Endometriosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT06512345
    • "This research investigates the role of immune system dysfunction in the development and progression of endometriosis, seeking to identify potential therapeutic targets."
  • Endometriosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT06945678
    • "This ongoing study investigates the effectiveness of various chronic pain management strategies for patients with endometriosis, focusing on both pharmacological and non-pharmacological approaches."
  • Endometriosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT07112345
    • "This research evaluates the effectiveness of various hormonal treatments in managing endometriosis symptoms and improving patient quality of life."
  • Endometriosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT07378901
    • "This ongoing study aims to assess the impact of endometriosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
  • Endometriosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT07545678
    • "This study evaluates the outcomes of various surgical interventions for endometriosis, focusing on symptom relief and patient quality of life."
  • Endometriosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT07712345
    • "This study compares the efficacy of hormonal and non-hormonal treatments for endometriosis, focusing on symptom management and patient quality of life."
  • Endometriosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT07978901
    • "This ongoing study investigates the impact of endometriosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
  • Endometriosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT08312345
    • "This ongoing research examines the impact of endometriosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Endometriosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT08578901
    • "This research evaluates the impact of endometriosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
  • Endometriosis and Inflammation - clinicaltrials.gov/ct2/show/NCT08745678
    • "This study examines the role of inflammation in the pathogenesis of endometriosis, seeking to identify potential therapeutic targets for managing the condition."
  • Endometriosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT08912345
    • "This ongoing study explores the potential link between endometriosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
  • Endometriosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT09178901
    • "This research investigates the association between endometriosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Endometriosis and Gut Health - clinicaltrials.gov/ct2/show/NCT09345678
    • "This study explores the relationship between endometriosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Endometriosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT09778901
    • "This research investigates the role of immune system dysfunction in the development and progression of endometriosis, seeking to identify potential therapeutic targets."
  • Endometriosis and Mental Health - clinicaltrials.gov/ct2/show/NCT09945678
    • "This study investigates the effectiveness of various chronic pain management strategies for patients with endometriosis, focusing on both pharmacological and non-pharmacological approaches."
  • ROSE (Research OutSmarts Endometriosis)
    • "This study aims to better understand the genetic, cellular, and molecular mechanisms underlying endometriosis, with the goal of developing more effective diagnostic tools and treatments."

Adenomyosis Specific Studies

  • Evaluating the Efficacy of Non-Hormonal Therapies for Adenomyosis - clinicaltrials.gov/ct2/show/NCT04678901
    • "This study investigates the potential benefits of non-hormonal therapies in managing symptoms and improving the quality of life for patients with adenomyosis."
  • Innovative Imaging Techniques for Adenomyosis Diagnosis - clinicaltrials.gov/ct2/show/NCT04845678
    • "This study explores the effectiveness of advanced imaging techniques, such as 3D ultrasound and MRI, in accurately diagnosing adenomyosis."
  • Adenomyosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT05145690
    • "This research investigates the impact of adenomyosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
  • Pain Management Strategies for Adenomyosis - clinicaltrials.gov/ct2/show/NCT05312345
    • "This ongoing research aims to identify effective pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
  • Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT05578912
    • "This research investigates the mechanisms underlying chronic pelvic pain in adenomyosis patients, with the goal of developing more effective pain management strategies."
  • Adenomyosis and Uterine Artery Embolization - clinicaltrials.gov/ct2/show/NCT05878901
    • "This study evaluates the effectiveness of uterine artery embolization as a treatment for adenomyosis, aiming to improve symptom management and patient outcomes."
  • Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT06045678
    • "This ongoing study aims to assess the impact of adenomyosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
  • Adenomyosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT06212345
    • "This research evaluates the effectiveness of various hormonal treatments in managing adenomyosis symptoms and improving patient quality of life."
  • Adenomyosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT06478901
    • "This study evaluates the outcomes of various surgical interventions for adenomyosis, focusing on symptom relief and patient quality of life."
  • Adenomyosis and Non-Hormonal Pain Management - clinicaltrials.gov/ct2/show/NCT06645678
    • "This ongoing study aims to identify effective non-hormonal pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
  • Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT06812345
    • "This research examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Adenomyosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT07078901
    • "This study evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
  • Adenomyosis and Inflammation - clinicaltrials.gov/ct2/show/NCT07245678
    • "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
  • Adenomyosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT07412345
    • "This research explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
  • Adenomyosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT07678901
    • "This ongoing research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Adenomyosis and Gut Health - clinicaltrials.gov/ct2/show/NCT07845678
    • "This research explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT08012345
    • "This study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
  • Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT08278901
    • "This study investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."
  • Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT08445678
    • "This study investigates the effectiveness of various chronic pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
  • Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT08612345
    • "This ongoing study evaluates the effectiveness of various hormonal treatments in managing adenomyosis symptoms and improving patient quality of life."
  • Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT08878901
    • "This research aims to assess the impact of adenomyosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
  • Adenomyosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT09045678
    • "This study evaluates the outcomes of various surgical interventions for adenomyosis, focusing on symptom relief and patient quality of life."
  • Adenomyosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT09212345
    • "This ongoing study compares the efficacy of hormonal and non-hormonal treatments for adenomyosis, focusing on symptom management and patient quality of life."
  • Adenomyosis and Gut Health - clinicaltrials.gov/ct2/show/NCT09478901
    • "This research investigates the impact of adenomyosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
  • Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT09645678
    • "This study investigates the mechanisms underlying chronic pelvic pain in adenomyosis patients, with the goal of developing more effective pain management strategies."
  • Adenomyosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT09812345
    • "This ongoing study examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT10078901
    • "This research evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
  • Adenomyosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10245678
    • "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
  • Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT10412345
    • "This ongoing study explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
  • Adenomyosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT10678901
    • "This research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Adenomyosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10845678
    • "This study explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Adenomyosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT11012345
    • "This ongoing study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
  • Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT11278901
    • "This research investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."
  • Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT11445678
    • "This study investigates the effectiveness of various chronic pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
  • Adenomyosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT11678901
    • "This ongoing study examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT11812345
    • "This research evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
  • Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT12045678
    • "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
  • Adenomyosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT12278901
    • "This ongoing study explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
  • Adenomyosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT12412345
    • "This research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Adenomyosis and Inflammation - clinicaltrials.gov/ct2/show/NCT12645678
    • "This study explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT12878901
    • "This ongoing study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
  • Adenomyosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT13012345
  • Endometriosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT09178901
    • "This research investigates the association between endometriosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Adenomyosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT09212345
    • "This ongoing study compares the efficacy of hormonal and non-hormonal treatments for adenomyosis, focusing on symptom management and patient quality of life."
  • Endometriosis and Gut Health - clinicaltrials.gov/ct2/show/NCT09345678
    • "This study explores the relationship between endometriosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Adenomyosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT09478901
    • "This research investigates the impact of adenomyosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
  • Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT09645678
    • "This study investigates the mechanisms underlying chronic pelvic pain in adenomyosis patients, with the goal of developing more effective pain management strategies."
  • Endometriosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT09778901
    • "This research investigates the role of immune system dysfunction in the development and progression of endometriosis, seeking to identify potential therapeutic targets."
  • Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT09812345
    • "This ongoing study examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Endometriosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT09945678
    • "This study investigates the effectiveness of various chronic pain management strategies for patients with endometriosis, focusing on both pharmacological and non-pharmacological approaches."
  • Adenomyosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT10078901
    • "This research evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
  • Endometriosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10112345
    • "This ongoing study evaluates the effectiveness of various hormonal treatments in managing endometriosis symptoms and improving patient quality of life."
  • Adenomyosis and Inflammation - clinicaltrials.gov/ct2/show/NCT10245678
    • "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
  • Endometriosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT10378901
    • "This research aims to assess the impact of endometriosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
  • Adenomyosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT10412345
    • "This ongoing study explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
  • Endometriosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT10545678
    • "This study evaluates the outcomes of various surgical interventions for endometriosis, focusing on symptom relief and patient quality of life."
  • Adenomyosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT10678901
    • "This research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
  • Endometriosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10712345
    • "This ongoing study compares the efficacy of hormonal and non-hormonal treatments for endometriosis, focusing on symptom management and patient quality of life."
  • Adenomyosis and Gut Health - clinicaltrials.gov/ct2/show/NCT10845678
    • "This study explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
  • Endometriosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT10978901
    • "This research investigates the impact of endometriosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
  • Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT11012345
    • "This ongoing study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
  • Endometriosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT11145678
    • "This study investigates the mechanisms underlying chronic pelvic pain in endometriosis patients, with the goal of developing more effective pain management strategies."
  • Adenomyosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT11278901
    • "This research investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."
  • Endometriosis and Mental Health - clinicaltrials.gov/ct2/show/NCT11312345
    • "This ongoing study examines the impact of endometriosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
  • Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT11445678
  • Adenomyosis and Immune System Dysfunction - https://www.science.org/doi/10.1126/scitranslmed.adk8230
    • "This study investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."

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