diff --git a/setup.py b/setup.py
index d9b8a911f..ab4a5097e 100644
--- a/setup.py
+++ b/setup.py
@@ -25,34 +25,19 @@
     # The core 'install_requires' should only be things
     # which are needed for the main editor to function.
     #
-    "PyQt5-sip<=12.13.0"
+    "PyQt5-sip<=12.17.0"
     + ';"arm" not in platform_machine and "aarch" not in platform_machine',
-    "PyQt5==5.13.2"
+    "PyQt5==5.15.11"
     + ';"arm" not in platform_machine and "aarch" not in platform_machine',
-    "QScintilla==2.11.3"
+    "QScintilla==2.14.1"
     + ';"arm" not in platform_machine and "aarch" not in platform_machine',
-    "PyQtChart==5.13.1"
+    "PyQtChart==5.15.7"
     + ';"arm" not in platform_machine and "aarch" not in platform_machine',
-    # FIXME: Needed for qtconsole, this is the latest wheel in armv7l for
-    # Python 3.7 (Buster), otherwise it tries to build from source and fails.
-    "pyzmq<=26.0.3",
-    # FIXME: jupyter-client added for Py3.5 compatibility, to be dropped after
-    # Mu v1.1 release. So, qtconsole < 5 and jupyter-client < 6.2 (issue #1444)
-    "jupyter-client>=4.1,<6.2",
-    # FIXME: ipykernel max added for macOS 10.13 compatibility, min taken from
-    # qtconsole 4.7.7. Full line can be removed after Mu v1.1 release.
-    # Dependency mirrored for user venv in mu/wheels/__init__.py
-    "ipykernel>=4.1,<6",
-    # FIXME: ipykernel<6 depends on ipython_genutils, but it isn't explicitly
-    # declared as a dependency. It also depends on traitlets, which
-    # incidentally brought ipython_genutils, but in v5.1 it was dropped, so as
-    # a workaround we need to manually specify it here.
-    "ipython_genutils>=0.2.0",
-    "qtconsole==4.7.7",
+    "qtconsole==5.6.1",
     #
     # adafruit-board-toolkit is used to find serial ports and help identify
     # CircuitPython boards in the CircuitPython mode.
-    "adafruit-board-toolkit~=1.1",
+    "adafruit-board-toolkit~=1.1.2",
     "pyserial~=3.5",
     "nudatus>=0.0.3",
     # `flake8` is actually a testing/packaging dependency that, among other
@@ -80,6 +65,10 @@
     # Needed to resolve an issue with paths in the user virtual environment
     #
     "pywin32; sys_platform=='win32'",
+    # PyGame
+    "pygame==2.6.1",
+    # PyGameZero
+    "pgzero==1.2.1",
 ]
 
 
@@ -133,7 +122,7 @@
         "mu.modes.api",
         "mu.wheels",
     ],
-    python_requires=">=3.5,<3.9",
+    python_requires=">=3.10,<3.13",
     install_requires=install_requires,
     extras_require=extras_require,
     package_data={"mu.wheels": ["*.whl", "*.zip"]},