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Description
Longitudinal sequencing from individuals with prolonged SARS-CoV-2 has some different attributes than spot sequencing of individual cases. Can the metadata standards be updated to handle longitudinal sampling?
Some considerations:
- How should prolonged infections be differentiated from reinfections?
- For prolonged infections, could
symptom_onset_datebe elevated to required when a prolonged infection is suspected, so that sample timing relative to initial symptom onset can be computed? - Can this information be mapped to Biosample submissions so that NCBI datasets from known prolonged infections can be readily identified?
Thanks!
dave
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