diff --git a/src/superqt/utils/_img_utils.py b/src/superqt/utils/_img_utils.py
index d5a920dc..c82ae089 100644
--- a/src/superqt/utils/_img_utils.py
+++ b/src/superqt/utils/_img_utils.py
@@ -1,3 +1,4 @@
+import sys
 from typing import TYPE_CHECKING
 
 from qtpy.QtGui import QImage
@@ -37,4 +38,8 @@ def qimage_to_array(img: QImage) -> "np.ndarray":
     arr = np.frombuffer(b, np.uint8).reshape(h, w, c)
 
     # reverse channel colors for numpy
-    return arr.take([2, 1, 0, 3], axis=2)
+    # On big endian we need to specify a different order
+    if sys.byteorder == "big":
+        return arr.take([1, 2, 3, 0], axis=2)  # pragma: no cover
+    else:
+        return arr.take([2, 1, 0, 3], axis=2)