Skip to content

Conversation

Congm12
Copy link
Contributor

@Congm12 Congm12 commented Dec 10, 2024

  • In case spaceranger outputs contain unzipped barcodes.tsv instead of barcodes.tsv.gz, add a check in calicos.smk to handle both cases.
  • In case the cellsnp-lite and eagle2 outputs contain a large number of SNPs and spots/cells that can't be loaded in a dense matrix, the utils/get_snp_matrix.py code in the preprocessing step is updated to combine eagle2 phasing into cellsnp-lite genotyping using all sparse matrix operations, which eventually outputs eagle2-phased A allele count and B allele count sparse matrices.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

1 participant