Data visualization and analysis for the mu opioid receptor biased agonism study in rhesus macaques.
View the Data Visualizations: vallenderlab.github.io/mu-paper-dataviz/
This repository contains code and data visualizations for the publication "In Vitro Effects of Ligand Bias on Primate Mu Opioid Receptor Downstream Signaling" (Zhang et al., 2020). The research characterizes MOR ligand bias in rhesus macaques, comparing signaling bias patterns across different agonists and validating the translational utility of nonhuman primate models.
If you use this repository, please cite:
Zhang X, Hutchins SD, Blough BE, Vallender EJ. In vitro effects of ligand bias on primate mu opioid receptor downstream signaling. Int J Mol Sci. 2020 Jun 3;21(11):E3999. DOI: 10.3390/ijms21113999